{"id":3763,"date":"2020-10-13T07:29:19","date_gmt":"2020-10-13T06:29:19","guid":{"rendered":"https:\/\/www.ab-science.com\/pipeline\/masitinib-overview\/"},"modified":"2021-10-20T14:05:16","modified_gmt":"2021-10-20T13:05:16","slug":"masitinib-apercu","status":"publish","type":"page","link":"https:\/\/www.ab-science.com\/fr\/pipeline\/masitinib-apercu\/","title":{"rendered":"Masitinib"},"content":{"rendered":"

[vc_row][vc_column width=\u00a0\u00bb1\/3″][vc_single_image image=\u00a0\u00bb1385″ img_size=\u00a0\u00bbfull\u00a0\u00bb alignment=\u00a0\u00bbcenter\u00a0\u00bb][\/vc_column][vc_column width=\u00a0\u00bb2\/3″][vc_column_text]Le masitinib est un inhibiteur de kinases oral, le premier de sa cat\u00e9gorie<\/em>, dont le m\u00e9canisme d’action est r\u00e9volutionnaire puisqu’il cible s\u00e9lectivement les mastocytes et les macrophages\/microglies.<\/p>\n

Sur la base de ce m\u00e9canisme d’action, le masitinib r\u00e9pond \u00e0 plusieurs indications en neurologie, dans les maladies inflammatoires et oncologiques. Certaines indications poursuivies avec le masitinib ont un potentiel de blockbuster (COVID-19<\/a>, maladie d’Alzheimer<\/a>, scl\u00e9rose en plaques<\/a>, asthme s\u00e9v\u00e8re<\/a>, cancer de la prostate<\/a><\/strong>), tandis que d’autres sont des maladies orphelines (scl\u00e9rose lat\u00e9rale amyotrophique<\/a>, mastocytose syst\u00e9mique indolente<\/a> <\/strong>et cancer du pancr\u00e9as<\/strong><\/a>).[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column width=\u00a0\u00bb1\/3″][vc_single_image image=\u00a0\u00bb1385″ img_size=\u00a0\u00bbfull\u00a0\u00bb alignment=\u00a0\u00bbcenter\u00a0\u00bb][\/vc_column][vc_column width=\u00a0\u00bb2\/3″][vc_column_text]Le masitinib est un inhibiteur de kinases oral, le premier de sa cat\u00e9gorie, dont le m\u00e9canisme d’action est r\u00e9volutionnaire puisqu’il cible s\u00e9lectivement les mastocytes et les macrophages\/microglies. Sur la base de ce m\u00e9canisme d’action, le masitinib r\u00e9pond \u00e0 plusieurs indications en neurologie, dans les maladies inflammatoires et oncologiques. Certaines indications…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":5917,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3763","page","type-page","status-publish","hentry","description-off"],"yoast_head":"\nMasitinib – AB Science<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ab-science.com\/fr\/pipeline\/masitinib-apercu\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Masitinib\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column width=\u00a0\u00bb1\/3″][vc_single_image image=\u00a0\u00bb1385″ img_size=\u00a0\u00bbfull\u00a0\u00bb alignment=\u00a0\u00bbcenter\u00a0\u00bb][\/vc_column][vc_column width=\u00a0\u00bb2\/3″][vc_column_text]Le masitinib est un inhibiteur de kinases oral, le premier de sa cat\u00e9gorie, dont le m\u00e9canisme d’action est r\u00e9volutionnaire puisqu’il cible s\u00e9lectivement les mastocytes et les macrophages\/microglies. Sur la base de ce m\u00e9canisme d’action, le masitinib r\u00e9pond \u00e0 plusieurs indications en neurologie, dans les maladies inflammatoires et oncologiques. 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